drugset / Trial / NCT01241097
Pleiotropism of Statin Therapy in High Dose Versus Low Dose Combined With Ezetimibe
RandomizedParallel-groupTriple-blind
Summary
* To test the hypothesis that therapy with high dose statin provides endothelial superior benefit to the same cholesterol lowering with low-dose statin combined with ezetimibe. * To test the hypothesis that therapy with high dose statin provides anti-inflammatory effect than the same reduction of cholesterol with low dose of statin plus ezetimibe
Timeline
- Start
- 2010-03
- Primary completion
- 2010-12
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ezetimibe | Unknown | 10 mg | — |
| Subject | Simvastatin | Small molecule | 10 mg | — |
| Subject | Simvastatin | Small molecule | 80 mg | — |
Indications
No indication recorded.