drugset / Trial / NCT01249872

Patients-Controlled Epidural Analgesia After Gastric Bypass for Morbid Obesity Using Morphine-Levobupivacaine Regimens

NCT01249872

Phase 2/3 Completed 96 enrolled University of Patras
RandomizedParallel-groupDouble-blindTreatment

Summary

Adequate postoperative analgesia can facilitate recovery following gastric bypass surgery for morbid obesity. The efficacy and safety of intravenous patient - controlled analgesia has been studied, but up to date no data are available concerning the use of thoracic epidural patient-controlled analgesia regarding the use of levobupivacaine combined with morphine in morbidly obese patients. The investigators' aim in this prospective, randomized, double-blinded study was to compare the analgesic effectiveness, the dose requirements and side effects of thoracic epidural patient controlled analgesia 0.1% and 0.2% levobupivacaine combined with a continuous epidural administration of morphine, with or without a loading dose, after open gastric bypass for morbid obesity.

Timeline

Start
2010-01
Primary completion
2012-08
Completion
2012-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator Levobupivacaine Other / unclassified 0.1 % Other
Comparator Levobupivacaine Other / unclassified 0.2 % Other
Comparator Morphine Other / unclassified 0.2 mg Other

Indications