drugset / Trial / NCT01261078
The Bupivacaine Dose Sparing Effect of Intrathecal Epinephrine
RandomizedParallel-groupDouble-blind
Summary
Intrathecal epinephrine has been known to increase the duration of spinal anesthesia, or increase the quality of anesthesia. However, there is still a controversy, and the mechanism of epinephrine is recently suggested as a modulator of pain information in the spinal cord. Therefore, the investigators try to investigate the dose sparing effect of intrathecal epinephrine for spinal anesthesia with bupivacaine.
Timeline
- Start
- 2010-12
- Primary completion
- 2011-07
- Completion
- 2011-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Epinephrine | Other / unclassified | 25 ug | Other |
| Comparator | Epinephrine | Other / unclassified | 50 ug | Other |
| Comparator | Epinephrine | Other / unclassified | 0.1 mg | Other |
| Comparator | Epinephrine | Other / unclassified | 200 ug | Other |
| Comparator | Bupivacaine | Other / unclassified | 8 mg | Other |
Indications
No indication recorded.