drugset / Trial / NCT01266057

Sirolimus or Vorinostat and Hydroxychloroquine in Advanced Cancer

NCT01266057

Phase 1 Completed 143 enrolled M.D. Anderson Cancer Center
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The goal of this clinical research study is to find the highest tolerable dose of sirolimus or vorinostat that can be given in combination with hydroxychloroquine to patients with advanced cancer. The safety of these drug combinations will also be studied.

Timeline

Start
2011-04-28
Primary completion
2021-02-11
Completion
2021-02-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Hydroxychloroquine Small molecule 200 mg Oral
Subject Sirolimus Small molecule 2 mg Oral
Subject Vorinostat Small molecule 200 mg Oral