drugset / Trial / NCT01291654

Paracetamol and Patent Ductus Arteriosus (PDA)

NCT01291654

Phase 2 Unknown 80 enrolled Shaare Zedek Medical Center
RandomizedCrossoverTriple-blindTreatment

Summary

The investigators propose that paracetamol will be similarly effective to ibuprofen in treating PDA in the premature neonate, with fewer side effects.

Timeline

Start
2012-04
Primary completion
2014-12
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 15 mg/kg Oral
Subject Ibuprofen Small molecule 5 mg/kg Intravenous
Subject Indomethacin Small molecule 2 mg/kg Intravenous