drugset / Trial / NCT01303731

Comparison of Standard and Minidose Spinal Anesthesia for Cesarean Section Operation Using Marcaine Spinal 0.5% Heavy

NCT01303731 ↗

Phase 4 Unknown 100 enrolled Bnai Zion Medical Center
RandomizedParallel-groupSingle-blindTreatment

Summary

The objectives of this study is to test a combination of low dose local anesthetic Bupivacaine diluted in patient's CSF with lipophilic opiate Fentanyl for optimal spinal anesthesia during Cesarean Section. The dilution of Bupivacaine with CSF in our study would result in effective spinal anesthesia with relatively limited motor block, quick recovery of motor function and relatively long lasting analgesia. We expect lower incidence of side effects with this combination than with convenient dose of Bupivacaine.

Timeline

Start
2011-02
Primary completion
2012-01
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupivacaine Other / unclassified 7.5 mg Intrathecal
Subject Bupivacaine Other / unclassified 12.5 mg Intrathecal
Subject Fentanyl Other / unclassified 12.5 ug Intrathecal