Sedation in Endoscopic Retrograde Cholangiopancreatography (ERCP) With or Without Opioids

Summary

Addition of fentanyl or remifentanil to the propofol produced sedation for scheduled ERCP will decrease the propofol requirements for predetermined sedation levels (as shown by Bispectral Index Monitor (BIS) monitor), will be associated with faster recovery monitored by Ramsay's and Observer's Assessment of Alertness/Sedation (OAAS) scores and BIS, less postoperative pain (assessed by Visual Analogue Scale=VAS) and less early cognitive impairment after sedation (as assessed by the MiniMental test).

Timeline

Start

2011-02

Primary completion

2013-01

Completion

2013-07

Publications

• Fassoulaki A, Iatrelli I, Vezakis A, Polydorou A. Deep sedation for endoscopic cholangiopancreatography with or without pre or intraprocedural opioids: A double-blind randomised controlled trial. Eur J Anaesthesiol. 2015 Sep;32(9):602-8. doi: 10.1097/EJA.0000000000000187.

Drugs

Indications