drugset / Trial / NCT01307306
Glucose Control in Severely Burned Patients
RandomizedParallel-groupSingle-blindTreatment
Summary
The central aim of this application is to determine whether improved outcomes with tight euglycemic control are due to insulin-specific responses. The investigators hypothesize that improving insulin resistance will lead to decreased inflammatory and hypermetabolic responses, as well as restored glucose metabolism, and so result in improved clinical outcome of severely burned patients.
Timeline
- Start
- 2011-03
- Primary completion
- 2018-03
- Completion
- 2018-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Insulin | Protein / enzyme biologic | — | Intravenous |
| Subject | Metformin | Small molecule | 850 mg | — |
Indications
No indication recorded.