drugset / Trial / NCT01336543

Consolidation Chemotherapy/Concurrent Chemo-radiotherapy for Inoperable Stage III Non-small Cell Lung Cancer (NSCLC)

NCT01336543 ↗

Phase 2 Withdrawn Syed Jafri
NaSingle-groupOpen-labelTreatment

Summary

This is a pilot phase II study of histology based consolidation chemotherapy in patients with inoperable stage III Non-Small Cell Lung Cancer (NSCLC) following concurrent chemo-radiotherapy. Patients with inoperable stage III NSCLC would be treated with standard concurrent chemo-radiotherapy and subsequently those with non-squamous histology would be offered 4 cycles of consolidation pemetrexed and those with squamous histology 4 cycles of consolidation with gemcitabine.

Timeline

Start
2011-03
Primary completion
2013-07
Completion
2013-07

Outcome

Outcome not reported

Stopped (Enrollment): “Low accrual, small patient population at center.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 1000 mg/m2 —
Subject Pemetrexed Small molecule 500 mg/m2 —
Background Cisplatin Other / unclassified 50 mg/m2 —
Background Etoposide Small molecule 80 mg/m2 —