Pharmacodynamic Clinical Trial of Cardiovascular Polypill on LDL Cholesterol

Summary

This study evaluates the effect on LDL cholesterol of the 3 drugs given together in the cardiovascular fixed dose combination pill (acetylsalicylic acid, simvastatin, and ramipril) as compared to the effect on LDL cholesterol of the reference products (simvastatin, ramipril, acetylsalicylic acid) Approximately 350 subjects will be screened, 266 randomized in order about 238 subjects to finish the study.

Timeline

Start

2010-10

Primary completion

2012-04

Completion

2012-04

Drugs

Indications