drugset / Trial / NCT01367210

Switch to Darunavir/r + Maraviroc Quaque Die in Patients With R5 Tropism by Viral DNA Genotyping (GUSTA)

NCT01367210

Phase 4 Terminated 165 enrolled Catholic University of the Sacred Heart
RandomizedParallel-groupOpen-labelTreatment

Summary

Objectives of the study: 1. To verify the safety and the efficacy of the study treatment, defined as the persistent control of the virus' replication at 48 weeks after the simplification to maraviroc + darunavir with ritonavir in patients with R5 tropism by viral DNA genotyping. 2. To collect relevant information about the safety, the immunologic and the economic impact of this strategy.

Timeline

Start
2011-06
Primary completion
2015-06
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Darunavir Small molecule 800 mg
Subject Maraviroc Other / unclassified 300 mg
Background Ritonavir Other / unclassified 100 mg