drugset / Trial / NCT01384279
The Therapeutic Effects of Topiramate and Metformin on Second Generation Antipsychotics-induced Obesity
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The primary aim of the study is to investigate the efficacy of metformin and topiramate on second-generation antipsychotic-induced obesity. The secondary domain we look at is the adverse effects of both drugs. The investigators hypothesize that metformin and topiramate are effective in treating obesity induced by second-generation antipsychotics.
Timeline
- Start
- 2011-05
- Primary completion
- 2011-12
- Completion
- 2012-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 1000 mg | — |
| Subject | Topiramate | Small molecule | 200 mg | — |