drugset / Trial / NCT01384279

The Therapeutic Effects of Topiramate and Metformin on Second Generation Antipsychotics-induced Obesity

NCT01384279

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary aim of the study is to investigate the efficacy of metformin and topiramate on second-generation antipsychotic-induced obesity. The secondary domain we look at is the adverse effects of both drugs. The investigators hypothesize that metformin and topiramate are effective in treating obesity induced by second-generation antipsychotics.

Timeline

Start
2011-05
Primary completion
2011-12
Completion
2012-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Metformin Small molecule 1000 mg
Subject Topiramate Small molecule 200 mg

Indications