drugset / Trial / NCT01397331
Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery
RandomizedParallel-groupDouble-blindTreatment
Summary
The aim of the study is to delineate and compare the changes in coupled mechanical properties of left ventricle and arterial vascular bed caused by two popular anesthetic protocols commonly used in cardiac surgery (intravenous, based on the infusion of propofol, versus inhalational, based on isoflurane) on different stages of the surgery.
Timeline
- Start
- 2010-07-01
- Primary completion
- 2012-06-27
- Completion
- 2012-06-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Isoflurane | Other / unclassified | 1 unknown | Inhaled |
| Comparator | Isoflurane | Other / unclassified | 1.5 unknown | Inhaled |
| Comparator | Propofol | Small molecule | 2 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 5 mg/kg | Intravenous |
| Comparator | Remifentanil | Small molecule | — | — |