drugset / Trial / NCT01436994
Antithyroid Drug Treatment of Thyrotoxicosis in Young People
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators aim to establish whether biochemical control during anti-thyroid drug therapy in young people with thyrotoxicosis varies depending upon whether a 'block and replace' or 'dose titration' regimen is used. The investigators will also assess remission rates and the frequency of side-effects in the two treatment groups.
Timeline
- Start
- 2004-07
- Primary completion
- 2014-12
- Completion
- 2015-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Carbimazole | Small molecule | 0.25 mg/kg | — |
| Comparator | Carbimazole | Small molecule | 0.75 mg/kg | — |
| Comparator | Levothyroxine | Other / unclassified | — | — |
| Comparator | Propylthiouracil | Small molecule | — | — |