drugset / Trial / NCT01466088

Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)

NCT01466088

Phase 2 Completed 386 enrolled Targacept Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Alzheimer's disease is the most common form of dementia and is the fourth leading cause of death among people 65 years of age and older. The global prevalence of the disease will increase significantly as the population ages, unless preventative treatments can be identified and marketed. The present study seeks to evaluate AZD3480 (TC-1734) compared to an approved medication (donepezil) shown to improve cognition and function in patients with Alzheimer's disease.

Timeline

Start
2011-10
Primary completion
2014-05
Completion
2014-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Donepezil Small molecule 10 mg Oral
Subject ispronicline Small molecule 30 mg Oral

Indications