drugset / Trial / NCT01489631
Analgesia After Total Knee Replacement Surgery
RandomizedParallel-groupOpen-labelSupportive care
Summary
Postoperative pain after total knee replacement surgery is difficult to treat. Mobilisation and hospital discharge might be delayed. Recent research shows that intra-articular infiltration with local anesthetics and perioperative prescription of gabapentin can improve outcome. Objective of the study: Comparison of mobilisation speed and postoperative NRS-scores of patients after total knee replacement surgery which is treated with epidural analgesia or peroperative infiltration of the knee. Appraisal of the value of gabapentin for reduction of postoperative opiate consumption.
Timeline
- Start
- 2013-03
- Primary completion
- 2014-04
- Completion
- 2014-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 0.125 % | Other |
| Comparator | Gabapentin | Small molecule | 300 mg | — |
| Comparator | Ropivacaine | Other / unclassified | 0.2 % | Other |
| Comparator | Ropivacaine | Other / unclassified | 50 ml | Other |
| Comparator | Sufentanil | Other / unclassified | 1 ug/ml | Other |
Indications
No indication recorded.