drugset / Trial / NCT01490229
Ezetimibe Versus Nutraceuticals in Statin-intolerant Patients
RandomizedParallel-groupSingle-blindTreatment
Summary
Pharmacologic alternatives in statin-intolerant patients include ezetimibe and nutraceuticals (i.e. compounds derived from foods with cholesterol lowering actions). The investigators will compare the efficacy and tolerability of ezetimibe versus a nutraceutical-based protocol in statin-intolerant patients treated with percutaneous coronary intervention.
Timeline
- Start
- 2013-01
- Primary completion
- 2014-12
- Completion
- 2016-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Berberine | Traditional medicine (herbal / TCM) | 500 mg | Oral |
| Comparator | Ezetimibe | Unknown | 10 mg | Oral |
| Subject | Policosanol | Small molecule | 10 mg | Oral |
| Subject | red yeast rice | Traditional medicine (herbal / TCM) | 200 mg | Oral |