drugset / Trial / NCT01507974

Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections

NCT01507974

Completed 220 enrolled HaEmek Medical Center, Israel
RandomizedParallel-groupOpen-labelTreatment

Summary

Urinary tract infection is the most common bacterial infection during pregnancy. Asymptomatic bacteriuria is the most common infection, in up to 8% of the population. Symptomatic infection may cause cystitis or cause pyelonephritis. Among pregnant women with recurrent bacteriuria, preventive antibiotic treatment has been found to be efficacious in reducing the bacteriuria rate and the complications. the changes of the urinary tract which appear during pregnancy usually resolve up to 3 months post-partum. The purpose of this study is to examine the efficacy of preventive antibiotic treatment during the puerperium.

Timeline

Start
2012-01-16
Primary completion
2014-07-01
Completion
2015-01-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Amoxicillin Other / unclassified 250 mg Oral
Comparator Amoxicillin Other / unclassified Oral
Comparator CEPHALEXIN ANHYDROUS Small molecule 500 mg Oral
Comparator Cefuroxime Small molecule 250 mg Oral
Comparator Clavulanate Unknown Oral
Comparator Nitrofurantoin Unknown 100 mg Oral
Comparator Sulfamethoxazole Small molecule Oral
Comparator Trimethoprim Small molecule Oral

Indications