drugset / Trial / NCT01507974
Examination of the Efficacy of Preventive Antibiotic Treatment During the Puerperium Among Pregnant Women With Recurrent Urinary Tract Infections
RandomizedParallel-groupOpen-labelTreatment
Summary
Urinary tract infection is the most common bacterial infection during pregnancy. Asymptomatic bacteriuria is the most common infection, in up to 8% of the population. Symptomatic infection may cause cystitis or cause pyelonephritis. Among pregnant women with recurrent bacteriuria, preventive antibiotic treatment has been found to be efficacious in reducing the bacteriuria rate and the complications. the changes of the urinary tract which appear during pregnancy usually resolve up to 3 months post-partum. The purpose of this study is to examine the efficacy of preventive antibiotic treatment during the puerperium.
Timeline
- Start
- 2012-01-16
- Primary completion
- 2014-07-01
- Completion
- 2015-01-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 250 mg | Oral |
| Comparator | Amoxicillin | Other / unclassified | — | Oral |
| Comparator | CEPHALEXIN ANHYDROUS | Small molecule | 500 mg | Oral |
| Comparator | Cefuroxime | Small molecule | 250 mg | Oral |
| Comparator | Clavulanate | Unknown | — | Oral |
| Comparator | Nitrofurantoin | Unknown | 100 mg | Oral |
| Comparator | Sulfamethoxazole | Small molecule | — | Oral |
| Comparator | Trimethoprim | Small molecule | — | Oral |