drugset / Trial / NCT01540487

Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /Metformin

NCT01540487

Phase 1 Completed 48 enrolled Boehringer Ingelheim
RandomizedCrossoverOpen-labelTreatment

Summary

The aim of the trial is to assess the relative bioavailability of fixed dose combination tablets of linagliptin and metformin compared to the administration of two single tablets (linagliptin and metformin ) in Chinese subjects. The availability of a fixed dose combination tablet is expected to significantly enhance patients' compliance with antidiabetic treatment., in particular with concern to the frequent polypharmacy in diabetic patients.

Timeline

Start
2012-02
Primary completion
2012-06
Completion
2012-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Linagliptin Small molecule 2.5 mg Oral
Subject Metformin Small molecule 500 mg Oral
Subject Metformin Small molecule 850 mg Oral

Indications

No indication recorded.