A Study of LY2189265 in Japanese Participants With Type 2 Diabetes Mellitus

Summary

The purpose of this trial is to examine the efficacy and safety of once-weekly LY2189265 in participants with type 2 diabetes mellitus who are not taking oral antidiabetic medication.

Timeline

Start

2012-03

Primary completion

2013-10

Completion

2014-05

Outcome

Met primary endpoint

registry analysis (superiority or other test); LY2189265 vs Placebo; p <0.001; LS Mean Difference -1.57 (95% CI -1.79 to -1.35); Mixed Models Analysis NCT01558271 ↗

Publications

• Iwamoto N, Matsui A, Kazama H, Oura T. Subgroup Analysis Stratified by Baseline Pancreatic beta-cell Function in a Japanese Study of Dulaglutide in Patients with Type 2 Diabetes. Diabetes Ther. 2018 Feb;9(1):383-394. doi: 10.1007/s13300-017-0346-4. Epub 2017 Dec 20.
• Suzuki S, Oura T, Takeuchi M, Boye KS. Evaluation of the impact of once weekly dulaglutide on patient-reported outcomes in Japanese patients with type 2 diabetes: comparisons with liraglutide, insulin glargine, and placebo in two randomized studies. Health Qual Life Outcomes. 2017 Jun 12;15(1):123. doi: 10.1186/s12955-017-0696-7.

Drugs

Indications