drugset / Trial / NCT01587430
3 Anthracyclines, 2 Types of Consolidation With Different ARA-C Doses and Maintenance in Adult Acute Myeloid Leukemia
RandomizedParallel-groupOpen-labelTreatment
Summary
The goal: to evaluate the role of high dose ara-c plus idarubicin and mitoxantrone consolidation followed by maintenance in the setting of high total cumulative anthracyclines dose(720-660 mg/m2).
Timeline
- Start
- 2010-01
- Primary completion
- 2014-04
- Completion
- 2015-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cytarabine | Small molecule | 1 g | — |
| Comparator | Cytarabine | Small molecule | 100 g | — |
| Comparator | Daunorubicin | Small molecule | — | — |
| Comparator | Idarubicin | Small molecule | 8 mg/m2 | — |
| Comparator | Mitoxantrone | Small molecule | 10 mg/m2 | — |