drugset / Trial / NCT01594489
Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction
RandomizedParallel-groupDouble-blindPrevention
Summary
The purpose of this study is to determine whether additional therapy with Aminophylline to hydration with sodium bicarbonate and administration of N-acetylcysteine is more effective to prevent contrast induced acute kidney injury in patients undergoing primary coronary intervention for acute ST elevation myocardial infarction.
Timeline
- Start
- 2009-01
- Primary completion
- 2012-09
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aminophylline | Small molecule | 200 mg | Intravenous |
| Comparator | N-acetylcisteine | Other / unclassified | 1200 mg | Intravenous |
| Comparator | sodium bicarbonate | Diagnostic / imaging agent | — | — |