drugset / Trial / NCT01729403

A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin

NCT01729403

Phase 2 Completed 57 enrolled Hoffmann-La Roche
RandomizedParallel-groupDouble-blindTreatment

Summary

This single-center, randomized, double-blind, placebo-controlled study will evaluate the effect of aleglitazar on insulin sensitivity in patients with type 2 diabetes mellitus who are inadequately controlled on metformin monotherapy. Patients will be randomized to receive either aleglitazar 150 mcg or placebo orally daily for 16 weeks, in addition to their existing dose and regimen of metformin.

Timeline

Start
2012-12
Primary completion
2013-09
Completion
2013-09

Drugs

EvaluationDrugModalityDoseRoute
Subject aleglitazar Small molecule 150 ug Oral
Background Metformin Small molecule