drugset / Trial / NCT01899066
Efficacy Study of Lucentis in the Treatment of Retinoblastoma
RandomizedSingle-groupOpen-labelTreatment
Summary
This study will evaluate the clinical efficacy of intravitreal injections of Ranibizumab (Lucentis) together with chemotherapy in the treatment of Retinoblastoma as compared to chemotherapy alone.
Timeline
- Start
- 2013-07
- Primary completion
- 2015-12
- Completion
- 2015-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ranibizumab | Monoclonal antibody | 0.5 mg | Intravitreal |
| Comparator | Carboplatin | Small molecule | 560 mg/m2 | — |
| Comparator | Etoposide | Small molecule | 150 mg/m2 | — |
| Comparator | Vincristine | Small molecule | 1.5 mg/m2 | — |