Added Value of Local Clonidine for Spine Postoperative Pain Control, in Addition to Bupivacaine

NCT01902108 ↗

Phase 4 Completed 225 enrolled St Joseph University, Beirut, Lebanon

RandomizedParallel-groupTriple-blindTreatment

Summary

The objective of this prospective randomized double-blind study is to evaluate the added analgesic value of clonidine to the conventional local bupivacaine wound infiltration in posterior spine surgery.

Timeline

Start: 2013-01
Primary completion: 2015-12
Completion: 2015-12

Publications

Abdel Hay J, Kobaiter-Maarrawi S, Tabet P, Moussa R, Rizk T, Nohra G, Okais N, Samaha E, Maarrawi J. Bupivacaine Field Block With Clonidine for Postoperative Pain Control in Posterior Spine Approaches: A Randomized Double-Blind Trial. Neurosurgery. 2018 Jun 1;82(6):790-798. doi: 10.1093/neuros/nyx313.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Clonidine	Other / unclassified	150 ug	Other
Comparator	Bupivacaine	Other / unclassified	0.25 %	Other
Comparator	Bupivacaine	Other / unclassified	20 ml	Other

Indications

No indication recorded.