A Phase II Trial of Adjuvant Radiotherapy Combined With Chemotherapy for Patients With High-risk Endometrial Cancer

NCT01918124 ↗

Phase 2 Completed 80 enrolled Fan Ming

NaSingle-groupOpen-labelTreatment

Summary

This phase II clinical trial was designed to assess the feasibility, safety, toxicity, recurrence and survival pattern when TP or CAP chemotherapy was combined with adjuvant radiation for patients with high-risk endometrial cancer.

Timeline

Start: 2008-01
Primary completion: 2013-01
Completion: 2014-01

Publications

Ren Y, Huang X, Shan B, Wu X, Huang X, Shi D, Wang H. Adjuvant concurrent chemoradiation followed by chemotherapy for high-risk endometrial cancer. Gynecol Oncol. 2016 Jan;140(1):58-63. doi: 10.1016/j.ygyno.2015.11.021. Epub 2015 Nov 24.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Carboplatin	Small molecule	5 unknown	—
Subject	Cisplatin	Other / unclassified	50 mg/m2	—
Subject	Cyclophosphamide	Other / unclassified	600 mg/m2	—
Subject	Doxorubicin	Other / unclassified	60 mg/m2	—
Subject	Paclitaxel	Small molecule	135 mg/m2	—

Indications

No indication recorded.