drugset / Trial / NCT01924234
Opioid Effects on Swallowing Comparing Younger and Elderly Volunteers
RandomizedCrossoverDouble-blindBasic science
Summary
The purpose of the study is to determine whether remifentanil influence the pharyngeal phase of swallowing using using pressure and impedance recordings. The purpose is also to compare remifentanil to morphine and younger to elderly volunteers.
Timeline
- Start
- 2013-08
- Primary completion
- 2014-12
- Completion
- 2014-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Morphine | Other / unclassified | 0.07 mg/kg | — |
| Comparator | Morphine | Other / unclassified | 0.1 mg/kg | — |
| Comparator | Remifentanil | Small molecule | 2 ng/ml | — |
| Comparator | Remifentanil | Small molecule | 3 ng/ml | — |
| Comparator | Remifentanil | Small molecule | 0.15 ug/kg | — |