drugset / Trial / NCT01964040
Perineural Dexmedetomidine and Femoral Nerve Block
Phase 4
Unknown
45 enrolled
Cairo University
Faculty of Medicine · collabanesthesia department · collab
RandomizedParallel-groupQuadruple-blindSupportive care
Summary
The duration of sensory block after single dose of long acting local anesthetics is not sufficient to avoid the postoperative use of opioids. Alpha-2 adrenoceptor agonists such as clonidine have been shown to increase the duration of peripheral nerve block. Dexmedetomidine is a more potent and selective α-2-adrenoceptor compared to clonidine. To the best of our knowledge, the use of Dexmedetomidine as adjuvant to local anesthetic was not previously reported for femoral nerve block.
Timeline
- Start
- 2013-08
- Primary completion
- 2013-12
- Completion
- 2014-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexmedetomidine | Other / unclassified | 50 ug | Other |
| Background | Bupivacaine | Other / unclassified | 15 ml | Other |
Indications
No indication recorded.