Multimodal Analgesic Treatment Versus Traditional Morphine Analgesia After Cardiac Surgery

NCT01966172 ↗

Phase 4 Completed 180 enrolled Rigshospitalet, Denmark

RandomizedParallel-groupSingle-blindTreatment

Summary

To test if multimodal analgesia with different analgesic medication offer better pain relief, lesser side effects and is safe compared to conventionel opiod analgesia after cardiac surgery.

Timeline

Start: 2007-03
Primary completion: 2009-08
Completion: 2009-12

Publications

Rafiq S, Steinbruchel DA, Wanscher MJ, Andersen LW, Navne A, Lilleoer NB, Olsen PS. Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial. J Cardiothorac Surg. 2014 Mar 20;9:52. doi: 10.1186/1749-8090-9-52.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Gabapentin	Small molecule	300 mg	Oral
Subject	Ibuprofen	Small molecule	400 mg	Oral
Comparator	Morphine	Other / unclassified	10 mg	Oral
Background	Acetaminophen	Small molecule	1000 mg	Oral

Indications

No indication recorded.