drugset / Trial / NCT01968317
Megestrol Acetate Plus Metformin to Megestrol Acetate in Patients With Endometrial Atypical Hyperplasia or Early Stage Endometrial Adenocarcinoma
Phase 2
Completed
150 enrolled
Xiaojun Chen
Fudan University · collabShanghai 6th People's Hospital · collabShanghai Changning Maternity & Infant Health Hospital · collabZhejiang Cancer Hospital · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to see if megestrol acetate plus metformin will be more effective in returning the endometrial tissue to a normal state than megestrol acetate alone in patients with endometrial atypical hyperplasia or early stage endometrial adenocarcinoma.
Timeline
- Start
- 2013-10
- Primary completion
- 2017-10
- Completion
- 2017-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Megestrol Acetate | Other / unclassified | 160 mg | Oral |
| Subject | Metformin | Small molecule | 500 mg | Oral |