drugset / Trial / NCT01990781

Effect of Intravenous Lidocaine and Dexamethasone Combination on Postoperative Sore Throat, Cough and Hoarseness.

NCT01990781 ↗

Phase 4 Completed 180 enrolled B.P. Koirala Institute of Health Sciences
RandomizedParallel-groupTriple-blindTreatment

Summary

Post operative sore throat (POST) following tracheal intubation is a common problem causing dissatisfaction and discomfort to the patients. Prophylactic use of both lidocaine and dexamethasone has been used independently for this purpose. However, there is no study assessing the synergistic analgesic effects of lidocaine and dexamethasone for POST. The purpose of this study is to compare the effect of lidocaine, dexamethasone and lidocaine dexamethasone combination on the incidence and severity of POST.

Timeline

Start
2013-12
Primary completion
2015-12
Completion
2016-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 8 mg Intravenous
Comparator Lidocaine Other / unclassified 1.5 mg/kg Intravenous

Indications

No indication recorded.