drugset / Trial / NCT02001883
Low-dose Statins and Nutraceuticals in High-intensity Statin-intolerant Patients
RandomizedParallel-groupSingle-blindTreatment
Summary
The primary objective of this study is to compare the efficacy and tolerability of low-dose statin therapy vs. the association between a low-dose statin and a nutraceutical-based protocol in high-dose statin-intolerant patients with coronary artery disease deemed to be at high-risk.
Timeline
- Start
- 2013-11
- Primary completion
- 2014-12
- Completion
- 2015-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atorvastatin | Small molecule | 5 mg | — |
| Comparator | Atorvastatin | Small molecule | 10 mg | — |
| Comparator | Berberine | Traditional medicine (herbal / TCM) | 500 mg | — |
| Comparator | Policosanol | Small molecule | 10 mg | — |
| Comparator | Simvastatin | Small molecule | 10 mg | — |
| Comparator | Simvastatin | Small molecule | 20 mg | — |
| Comparator | red yeast rice | Traditional medicine (herbal / TCM) | 200 mg | — |