drugset / Trial / NCT02013453
A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine if the addition of proton pump inhibitors (PPIs) to standard chemotherapy can improve progression free survival in patients with head and neck cancer.
Timeline
- Start
- 2013-12
- Primary completion
- 2016-12
- Completion
- —
Outcome
Outcome not reported
Stopped (Business): “Lack of funding”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Omeprazole | Other / unclassified | 40 mg | Oral |
| Background | Carboplatin | Small molecule | — | Other |
| Background | Paclitaxel | Small molecule | — | Other |
| Background | Pemetrexed | Small molecule | — | Other |
| Background | fluorouracil | Small molecule | — | Other |