drugset / Trial / NCT02016924

Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV

NCT02016924

Phase 2/3 Active not recruiting 133 enrolled Gilead Sciences
Non-randomizedSequentialOpen-labelTreatment

Summary

The goal of this clinical study is to learn more about the safety and dosing of study drugs, cobicistat-boosted Atazanavir (ATV/co), cobicistat-boosted darunavir (DRV/co) and emtricitabine/tenofovir alafenamide (F/TAF), in children (age ≥ 4 weeks to \< 18 years) with HIV.

Timeline

Start
2014-01-16
Primary completion
2025-06-13
Completion
2027-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Atazanavir Other / unclassified Oral
Subject Cobicistat Small molecule 30 mg Oral
Subject Cobicistat Small molecule 90 mg Oral
Subject Cobicistat Small molecule 150 mg Oral
Subject Darunavir Small molecule Oral
Subject emtricitabine Other / unclassified 15 mg Oral
Subject emtricitabine Other / unclassified 30 mg Oral
Subject emtricitabine Other / unclassified 60 mg Oral
Subject emtricitabine Other / unclassified 120 mg Oral
Subject emtricitabine Other / unclassified 200 mg Oral
Subject tenofovir alafenamide Small molecule 1.88 mg Oral
Subject tenofovir alafenamide Small molecule 3.75 mg Oral
Subject tenofovir alafenamide Small molecule 7.5 mg Oral
Subject tenofovir alafenamide Small molecule 15 mg Oral
Subject tenofovir alafenamide Small molecule 25 mg Oral
Background Abacavir Other / unclassified
Background Didanosine Small molecule
Background Lamivudine Other / unclassified
Background Lopinavir Other / unclassified Oral
Background Stavudine Other / unclassified
Background Tenofovir disoproxil fumarate Small molecule
Background Zidovudine Small molecule

Indications