drugset / Trial / NCT02025426

Phenylephrine Versus Ephedrine in Pre-eclampsia

NCT02025426 ↗

Phase 4 Terminated 13 enrolled Duke University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Phenylephrine administration is associated with reductions in CO and SctO2 compared with ephedrine when used for blood pressure management in women with pre-eclampsia undergoing cesarean delivery under spinal anesthesia.

Timeline

Start
2012-09
Primary completion
2016-07-08
Completion
2016-07-08

Outcome

Outcome not reported

Stopped (Enrollment): “Significant challenges recruiting a difficult patient population with most surgeries occurring out of hours”

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ephedrine Small molecule — —
Comparator Phenylephrine Small molecule — —

Indications