drugset / Trial / NCT02123628
Antibiotic Treatment Duration for Non-Surgically-Treated Diabetic Foot Osteomyelitis
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of the study is to compare the efficacy and tolerance of 6- versus 12-week antibiotic therapy in patients with diabetic foot osteomyelitis treated medically.
Timeline
- Start
- 2007-06
- Primary completion
- 2010-06
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cefepime | Small molecule | 2 g | Intravenous |
| Comparator | Cefotaxime | Small molecule | 100 mg/kg | Intravenous |
| Comparator | Ceftriaxone | Other / unclassified | 2 g | Intravenous |
| Comparator | Ciprofloxacin | Small molecule | 750 mg | Intravenous |
| Comparator | Ciprofloxacin | Small molecule | 1000 mg | Intravenous |
| Comparator | Doxycycline | Small molecule | 200 mg | Oral |
| Comparator | Fusidic Acid | Unknown | 500 mg | Oral |
| Comparator | Levofloxacin | Small molecule | 500 mg | Intravenous |
| Comparator | Levofloxacin | Small molecule | 750 mg | Intravenous |
| Comparator | Linezolid | Other / unclassified | 600 mg | Intravenous |
| Comparator | Rifampin | Small molecule | 10 mg/kg | Other |
| Comparator | trimethoprim-sulfamethoxazole | Unknown | 800 mg | Intravenous |