drugset / Trial / NCT02130830

Topical Anesthesia Versus Placebo to Decrease Pain in Rubber Band Ligation for Treatment of Internal Hemorrhoids

NCT02130830

Phase 3 Completed 80 enrolled Pontificia Universidad Catolica de Chile
RandomizedSingle-groupTriple-blindTreatment

Summary

Rubber band ligation is a simple and effective procedure for the management of hemorrhoidal disease. However, 90% of patients have some degree of discomfort associated with the procedure and up to 40% develop clinically significant pain. Some studies have used local anesthesia to reduce pain with promising results, but the use of topical anesthesia has not been reported before. The investigators hypothesize that the use of topical anesthesia before rubber band ligation significantly reduces post procedure pain.

Timeline

Start
2014-05
Primary completion
2016-05
Completion
2016-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Lidocaine Other / unclassified 2.5 % Topical
Subject prilocaine Small molecule 2.5 % Topical

Indications