drugset / Trial / NCT02151461
Dose Comparisons of Leucine-Metformin Combinations on Blood Glucose Levels In Type 2 Diabetic Patients
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The goal of this study is to demonstrate that leucine in combination with a low does of metformin can serve as an adjunct to diet and exercise to improve blood glucose levels in type 2 diabetic subjects. This study will compare three doses of a leucine-metformin combination to the standard metformin dose in controlling blood glucose levels in type 2 diabetic patients.
Timeline
- Start
- 2014-07
- Primary completion
- 2015-08
- Completion
- 2016-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Metformin | Small molecule | 125 mg | — |
| Subject | Metformin | Small molecule | 250 mg | — |
| Subject | Metformin | Small molecule | 500 mg | — |
| Subject | Metformin | Small molecule | 850 mg | — |
| Subject | amino acids | Unknown | 1100 mg | — |