drugset / Trial / NCT02159807
Optimizing Dose of Bupivacaine in Combined Spinal Epidurals To Reduce Side Effects
RandomizedParallel-groupTriple-blindTreatment
Summary
The purpose of this study is to determine what dose of medication administered through a combined spinal epidural (CSE) provides the optimal pain relief with the minimal amount of side effects. The 3 doses studied here (1.25, 1.66 and 2.5mg) are routinely use on the labor floor (depending on the physician preference) but the idea is to quantify safety, efficacy and side effects for each of these doses.
Timeline
- Start
- 2015-04-24
- Primary completion
- 2017-12-29
- Completion
- 2017-12-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupivacaine | Other / unclassified | 1.25 mg | Intrathecal |
| Comparator | Bupivacaine | Other / unclassified | 1.66 mg | Intrathecal |
| Comparator | Bupivacaine | Other / unclassified | 2.5 mg | Intrathecal |
| Comparator | Fentanyl | Other / unclassified | 20 ug | Intrathecal |