drugset / Trial / NCT02161731
Study of Evacetrapib (LY2484595) and Warfarin in Healthy Participants
Non-randomizedSingle-groupOpen-labelBasic science
Summary
All study participants will receive both warfarin and a study drug called evacetrapib. The main purpose of this study is to look at how much warfarin gets into the blood stream and how long it takes the body to get rid of warfarin when given both with and without evacetrapib. Another purpose is to evaluate the effectiveness of warfarin therapy to prevent blood clots when given with evacetrapib by measuring the time it takes for blood to clot and comparing it to an average of the international normalized ratio (INR). INR measures the time it takes for blood to clot and compares it to an average. The study will last approximately 5 weeks, not including screening.
Timeline
- Start
- 2014-06
- Primary completion
- 2014-09
- Completion
- 2014-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Evacetrapib | Small molecule | — | Oral |
| Subject | Warfarin | Small molecule | 15 mg | Oral |
Indications
No indication recorded.