Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery

Summary

* It has been shown that patients who undergo liver resection surgery are at high risk for postoperative acute kidney injury (AKI). * Sevoflurane may increase the risk for postoperative AKI because of production of compound-A. * Therefore, we have planned to investigate the effects of different anesthetic agents on postoperative renal function. * Patients undergoing liver resection surgery are randomized into 2 groups. * One of the groups receives sevoflurane and the other group receives desflurane. * Blood and urine specimen are sampled both pre- and postoperatively, and several biomarkers are compared between the groups.

Timeline

Start

2014-07

Primary completion

2023-05

Completion

2023-05

Drugs

Indications