drugset / Trial / NCT02174913
Awakening in Spine Surgery: A Comparison Between Clinical Signs and Bispectral Index
RandomizedParallel-groupTriple-blindOther
Summary
BIS is one of several equipments used to monitor depth of anesthesia.Some studies found BIS can reduce total propofol dose when being used with target controlled infusion (TCI).The objective is to compare awakening time after spine surgery between using clinical signs and bispectral index (BIS) guided target controlled infusion(TCI) of propofol in patients having neurophysiologic monitoring.
Timeline
- Start
- 2014-05
- Primary completion
- 2016-02
- Completion
- 2016-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Propofol | Small molecule | 3 ug/ml | Intravenous |
| Comparator | Propofol | Small molecule | 7 ug/ml | Intravenous |
| Comparator | Atracurium | Small molecule | 0.6 mg/kg | — |
| Comparator | Fentanyl | Other / unclassified | 0.5 ug/kg | Intravenous |
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | Intravenous |