drugset / Trial / NCT02204345

A Study Evaluating RO5479599 in Combination With Carboplatin and Paclitaxel in Participants With Advanced or Metastatic Non-Small-Cell Lung Cancer (NSCLC) of Squamous Histology

NCT02204345

Phase 1/2 Terminated 12 enrolled Hoffmann-La Roche
NaSingle-groupOpen-labelTreatment

Summary

A multi-center Phase Ib/II study of the combination of RO5479599 with carboplatin and paclitaxel once in every 3 week (q3w) regimen to evaluate the safety and tolerability.

Timeline

Start
2014-10
Primary completion
2016-03
Completion
2016-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Lumretuzumab Monoclonal antibody 800 mg Intravenous
Background Carboplatin Small molecule Intravenous
Background Paclitaxel Small molecule 200 mg/m2 Intravenous