drugset / Trial / NCT02234466

Preoperative Oral Dexamethasone to Improve Recovery After Surgery

NCT02234466

Phase 2 Unknown 80 enrolled University of Manitoba
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Randomized controlled trial of pre-operative oral dexamethasone vs placebo for the improvement of quality of recovery from surgery. The study population is limited to breast surgery patients. The investigators will also look at the effect of our intervention on post operative nausea and vomiting. Patients will be recruited before the date of their surgery and will complete the Quality of Recovery-40 (QOR-40) questionnaire before their surgery and at 24 hours post op. They will also complete a Clinically significant nausea and vomiting score upon discharge from the post anesthesia recovery room, repeated at 24 hours post op.

Timeline

Start
2014-08
Primary completion
2015-03
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 10 mg Oral
Comparator Ondansetron Other / unclassified 6 mg Intravenous

Indications