drugset / Trial / NCT02289261
A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine whether dexmedetomidine added to morphine is effective in the treatment of chronic cancer pain.
Timeline
- Start
- 2014-11
- Primary completion
- 2015-02
- Completion
- 2015-02
Publications
- Background Blaudszun G, Lysakowski C, Elia N, Tramer MR. Effect of perioperative systemic alpha2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. Anesthesiology. 2012 Jun;116(6):1312-22. doi: 10.1097/ALN.0b013e31825681cb.
- Results Lin TF, Yeh YC, Lin FS, Wang YP, Lin CJ, Sun WZ, Fan SZ. Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia. Br J Anaesth. 2009 Jan;102(1):117-22. doi: 10.1093/bja/aen320. Epub 2008 Nov 5.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | 0.1 ug/kg | — |
| Comparator | Morphine | Other / unclassified | 0.02 mg/kg | — |