drugset / Trial / NCT02310997
Myloablative Cord Blood Transplant in Haematological Malignancies (MAC UCBT)
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This trial is looking at using umbilical cord blood from unrelated donors after high dose chemotherapy. It is for people who have cancer of the bone marrow or lymphatic system including leukaemia and lymphoma, or a blood disorder called myelodysplastic syndrome (MDS). The trial is for babies over 4 weeks old, children, and adults up to the age of 45.
Timeline
- Start
- 2011-07
- Primary completion
- 2015-05
- Completion
- 2015-05
Outcome
Outcome not reported
Stopped (Enrollment): “Trial closed early due to poor recruitment”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Busulfan | Small molecule | 3.2 mg/kg | — |
| Subject | Cyclophosphamide | Other / unclassified | 60 mg/kg | — |
| Subject | Fludarabine | Small molecule | 25 mg/m2 | — |
| Subject | Melphalan | Small molecule | 140 mg/m2 | — |