drugset / Trial / NCT02362256
The Comparison of Stress Response to Rapid Opioid Detoxification Applying Different Methods of Opioid Antagonism
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The aim of this study is to investigate which method of naltrexone induction during rapid opioid detoxification causes stronger stress response and has a higher influence on opioid abstinence caused by opioid induction.
Timeline
- Start
- 2014-05
- Primary completion
- 2014-06
- Completion
- 2014-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naltrexone | Small molecule | 12.5 mg | Oral |
| Background | Clonidine | Other / unclassified | 150 ug | Oral |
| Background | Lorazepam | Small molecule | 5 mg | Oral |