drugset / Trial / NCT02394418
Effect of Sevoflurane, Propofol and Dexmedetomidine on Delirium & Neuroinflammation in Mechanically Ventilated Patients
RandomizedParallel-groupSingle-blindTreatment
Summary
Assessment of sedative effects of sevoflurane, dexmedetomidine and propofol on the clinical course of delirium, SIRS and neuroinflammation in mechanically ventilated patients using CAM-ICU scale, GSK-3beta and protein S100b in serum.
Timeline
- Start
- 2017-09-01
- Primary completion
- 2018-05
- Completion
- 2018-08
Outcome
Outcome not reported
Stopped: “for technical reasons”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexmedetomidine | Other / unclassified | — | Intravenous |
| Comparator | Propofol | Small molecule | — | Intravenous |
| Comparator | Sevoflurane | Other / unclassified | — | Inhaled |