drugset / Trial / NCT02397486
The Impact of Pentoxifylline and Vitamin E on Radiotherapy-induced Toxicity in Head & Neck Cancer Patients
RandomizedParallel-groupOpen-labelPrevention
Summary
The purpose of this study is to determine whether pentoxifylline and vitamin E are effective in prevention of radiotherapy- induced toxicity in head and neck cancer patients treated with concurrent chemoradiotherapy.
Timeline
- Start
- 2015-05-02
- Primary completion
- 2018-06-30
- Completion
- 2018-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pentoxifylline | Small molecule | 400 mg | Oral |
| Subject | Vitamin E | Other / unclassified | 1000 mg | Oral |
| Background | Cisplatin | Other / unclassified | 100 mg/m2 | — |