drugset / Trial / NCT02397486

The Impact of Pentoxifylline and Vitamin E on Radiotherapy-induced Toxicity in Head & Neck Cancer Patients

NCT02397486

Phase 2 Completed 60 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelPrevention

Summary

The purpose of this study is to determine whether pentoxifylline and vitamin E are effective in prevention of radiotherapy- induced toxicity in head and neck cancer patients treated with concurrent chemoradiotherapy.

Timeline

Start
2015-05-02
Primary completion
2018-06-30
Completion
2018-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Pentoxifylline Small molecule 400 mg Oral
Subject Vitamin E Other / unclassified 1000 mg Oral
Background Cisplatin Other / unclassified 100 mg/m2