Peri-neural Dexmedetomidine as an Adjuvant to Bupivacaine Induced Paravertebral Block in Patients Undergonig Thoracotomy

Phase 2 Completed 40 enrolled Cairo University

RandomizedParallel-groupTriple-blindTreatment

Summary

This study evaluates the effect of adding dexmedetomidine as an adjuvant to bupivacaine in patients undergoing thoracotomy when administered peri-neurally in thoracic paravertebral space.

Timeline

Start: 2015-02
Primary completion: 2015-11
Completion: 2015-12

Publications

Results Marhofer D, Kettner SC, Marhofer P, Pils S, Weber M, Zeitlinger M. Dexmedetomidine as an adjuvant to ropivacaine prolongs peripheral nerve block: a volunteer study. Br J Anaesth. 2013 Mar;110(3):438-42. doi: 10.1093/bja/aes400. Epub 2012 Nov 15.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dexmedetomidine	Other / unclassified	50 ug	Other
Comparator	Bupivacaine	Other / unclassified	20 ml	Other

Indications

No indication recorded.